Friday, June 6, 2008

Anesthesia on Demand

My idea of “Demand Anesthesia” is not liked by many senior anesthesiologists including my late teacher Dr. Bhojraj. Their objection to this technique is that the patient responds in between which is likely to result in adrenaline secretion and may result in hypertension, ventricular fibrillation and arrest. Demand anesthesia is a vigilant anesthetic technique which needs continuous watch of the depth of anesthesia by signs of light anesthesia like

  • (a) tachycardia
  • (b) some muscle movements
  • (c)screwing of the eyebows and forehead.
When any one of the signs is exhibited you are supposed to administer additional dose of Thiopentone till the reflex is suppressed. Far too often appearance of signs of anesthesia means you have to give additional sedatives and analgesics like Diazepam and Pethidine or Pentazocin or even stronger pain relieving drugs. All one is supposed to do is the balance the quantity of drug given and reaction of the patient to the stimuli. People are really worried about the cumulative effect of drug in post op period. But the patients are comfortable. Their O2 saturation does not fall and if by any chance the effect of drug persists as trickle of O2 though the nasal catheters tides over. This technique has been tried in many nursing homes without Boyle’s apparatus to deliver Nitrous Oxide-Oxygen and inhalational anesthesia. In my practice I have extensively tried this technique especially in cystoscopic procedures and orthopedic procedures like major fractures in very aged patient. Surgeons are very happy with the procedures since they find their patients awake and comfortable in post-op period. Vital parameters (signs) are stable and well maintained. Though anesthesiologists do not believe in this technique, my advice to them is “to see and then believe”. Those who have seen this technique are converted and like the technique. In a difficult situation it comes in handy.

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Reporting your observations: Beyond the call?

A senior urologist had taken a patient aged 82 for cystoscopy. The surgeon was in some doubt about why he was doing the cystoscopy, but since the patient had complaints he did not want to miss anything serious. I was about to cannulate a vein for anesthesia on the left forearm which was abducted on a arm board when I noticed a thumb sized vein on the chest wall. I wanted him to see it. As soon as he saw it he know that he had missed something big. He removed his gloves and put his hand on the upper part of the abdomen. He later confirmed that it was a big gastric carcinoma with complete blockage of the vena cava. Needless to say, the scopy was abandoned.
My point is that your should report your observations to the surgeon. I asked my students whether they narrate their observations. Some did not respond, some said that it is not our job. In my opinion one of our duties is to guard the patient’s interest; if you observe anything significant report it since silence could harm the patient. When I taught, I presented my private practice cases to my students as problems, I asked them whether they would proceed with anesthesia, refuse anesthesia, or would they like to know what happened to the patient. I made them think about it and discuss it in the next meeting. In this manner they learned much more than what text books could teach them.

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Treating the whole patient

A close friend’s relative who had just returned from UK after his fellowship needed my help for an emergency. He wanted to transfuse the patient with at least 2 units and he gave me a call when the patient was ready. The nursing home was close to our house. When I arrived at the nursing home I was taken to the changing room. In the surgeon’s room I read the case paper. I checked with the ward boy to make sure that the paperwork belonged to the patient who was in for surgery. I glanced through the notes; the patient was about 38 years female. There was no mention about the menstrual history. When I went in the operation theater I noticed that the patient was very anxious about her survival and was worried about her son who was about 16-17 years and was by himself. I asked the surgeon about the menstrual history; he said that it was not relevant and it was not mentioned. He also said that the father of the son is a merchant marine (shippy /sailor) and has not come home for 3 years. Even then my diagnosis from the very look of the patient was different from their tentative diagnosis of a burst gall bladder. The planned incision was vertical, long parallel to the mid line extending from below the umbilicus to the costal margin. I suggested that they open the abdomen through the lower part of the planned incision (paraumbilical) and they agreed. They took about a 3 inch incision in the paraumbilical region with a further plan of extending it upwards. I was watching as the incision was made. The peritoneum in the paraumbilical regions looked black. I asked them to open the peritoneum and keep the suction ready. On opening, a black liquid gushed out and it filled the suction bottles. When the fluid was almost drained I requested them to extend the incision site down to symphysis pubis and feel for the tube-ovarian mass. They felt the mass which was brought out through the incision. This confirmed that it was a case of burst tubal pregnancy. They excised the mass and they were worried about the patient’s condition as the fluid drained was nearly 2 liters or more. I assured him that this is altered blood and the patient is well and they need not worry about the life of the patient. They administered a good peritoneal lavage and took out all the blood clots and closed the abdomen.
As we were having tea after the patient had been shifted to the bed, the team asked me about my diagnosis. My answer was the very look of the patient was diagnostic of burst tubal pregnancy and not that of a gall bladder rupture. I told them that this was my third case with similar circumstance and something I would not forget in my life time. Why had I asked them about menstrual history? Well…in a female patient usually it is recorded. Initially I had not suspected their diagnosis of gall bladder rupture but the very anxious look of patient, concern about her life, fully conscious, beads of perspiration on the face were very diagnostic as compared to burst gall bladder where the patient looks very toxic. That is also why I was continually looking at that small incision layer by layer and the black peritoneum clinched my diagnosis. The team told me that they are not going to tell the diagnosis to the patient but simply assure her that she would not be pregnant again (a great topic for a discussion on ethics in medicine) since they had ligated both the tubes. The patient must have understood and the son was not told about the bilateral tubal ligation as it would have been embarrassing.
In a similar case of exploratory laparotomy; all the surgeon knew is that had to open the abdomen to find the cause. The surgeon went to wash up; the patient was brought in a wheel chair. The patient was an anxious looking young female, sweating all over the body. I informed the surgeon about my suspected diagnosis of a tubal pregnancy and altered my method of anesthesia accordingly. The surgeon opened the abdomen to find the tubal pregnancy. Again, after the operation was completed and patient was shifted to the bed, the surgeon expressed his surprise about my diagnosis before the patient was opened. I had to tell him about the typical anxious look in a young female, full of perspiration all over and most importantly no toxicity.
You have to treat the whole patient.

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Saturday, May 24, 2008

Use new drugs with caution

Beware of new drugs being introduced in the market...The pharmacologist and the drug industry have to criticize the old drugs to replace them with new. They have criticized Thiopentone to make way for their costly drug-Propofol. They highlight the rapid recovery of consciousness, which can be advantageously used for operations for day care surgery. But one has to remember that its use as induction agent for a prolonged surgery has no meaning. Even Thiopentone is metabolised and excreted in that time. The cost of the new drug is very high. The solvent of the drug is Egg white and soya bean oil. One raises a doubt to inject a foreign protein I.V. that may land you with serious anaphylactoid reaction and death. Thus you have to weigh the advantages and disadvantages by discussing with your colleagues and not be misled by the medical representatives.
They are now trying to throw out Scoline by propagating single long acting muscle relaxant with increased initial dose to be used for intubation. They try to highlight the bad effects of Succinylcholine Chloride. But ask yourself a simple question “How many deaths have you heard or seen in clinical practice under Scoline.” Except in cases where the drug is definitely contra indicated with raised serum potassium due to any cause at least in my practice I have not come across a single case with death due to Scoline. The first successful drug Atracurium which was successfully launched to replace Scoline was found later to cause anaphylactoid reaction due to intubating dose. It was abandoned in Europe and was being dumped in India. Luckily better drugs appeared in the market and we in India were prevented from being guinea pigs.

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#36-40: Private Practice Anesthesia- Do’s and Dont’s


  1. Never start a case unless the surgeon has talked to the patient. The assistant may ask you to start under instructions from the surgeon who is not present on the premises.
  2. Make the surgeons or the anesthesiologist colleague aware of complications seen or heard by you prior, but as far as possible do not disclose the names of surgeon or anesthesiologist or hospital.
  3. Do not be shy to consult your senior in a difficult case and in the event of an accident try to find out the cause from as many sources until you are satisfied.
  4. Do not start anaesthesia or even give sedation if the patient is not accompanied with a relative or friend. It is only in such cases serious complication occurs.
  5. Remember myasthenic tendency in patients with long standing malignancy avoid using long acting muscle relaxant. If it has to be used, fractionate the dose and repeat only when absolute necessary. Tailor down the doses of all drugs that you are giving as these patients become very sensitive to all drugs.

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#31-35: Private Practice Anesthesia- Do’s and Dont’s


  1. Keep a casual watch on theatre asepsis and let the surgeon know at an appropriate time. Observe the colour changing labels on the drums, and instruments supplied in between.
  2. Always talk to the surgeon first in high risk cases where a death on table is likely. When surgeon agrees, talk to the relatives along with surgeon. Obtain consent, then only start.
  3. Patients with respiratory obstruction, difficulty in breathing, Ludwig’s angina trismus: In these cases do not even venture to give sedation. Never think of giving anaesthesia unless the airway is secured. Topical anaesthesia, awake intubation, tracheostomy done, guided blind intubation or flexible intubating bronchoscope used to intubate are your options.
  4. In places with very hot climate and during summer allow patients to have a glass of plain water one hour before surgery. This is especially for children.
  5. Do not order your premed for adults. Give IV at the induction only in sepcial cases. Order the premed at the exact time. Do not give only Ketamine to an adult. Do not give Diazepam alone for patient with pain. They become incoherent and unmanageable. Same rule follows for Scopolamine for elderly patients.

#36-40: Private Practice Anesthesia- Do’s and Dont’s

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#26-30: Private Practice Anesthesia- Do’s and Dont’s


  1. Patients who are obese, have thick necks, full set of teeth, micrognathia or receding chin present difficulties for intubation. Keep the nasal tube ready. If possible keep even laryngeal mask airway tube ready. Warn the surgeon and take his help. If nothing is possible attempt awake intubation under topical anaesthesia.
  2. Before handing over a patient on IPPR to any person even for a short period, see that he can do it in your presence. Ask him to observe the quick inflation of the chest. Instruct him that during your absence he must not leave the patient to attend to surgeon in charge or the nurse in charge. Do not depend on attending doctors; they may only observe the movements of the bellows. Explain to your hand-off person that that he is breathing for the patient and stoppage will kill the patient.
  3. When dealing with cases with high risk history of previous anaesthesia, ascertain the causes from whatever the patient tells you; consult his anesthesiologist if available.
  4. Try to help the theatre staff if you are comfortable at your end. Remind and observe the nurse for sponge count before and at the end of surgery. Keep a watch on asepsis as far as visitors go. All this in the interest of well being of the patient.
  5. Try to suggest the surgeon in difficulty. He may or may not agree. You may share your observations gained from previous cases.

#31-35: Private Practice Anesthesia- Do’s and Dont’s

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#21-25: Private Practice Anesthesia- Do’s and Dont’s


  1. Beware of precipitous fall of BP in cases with induction of GA with regular dose of Thiopentone in failed spinal or epidural.
  2. Patients with diabetes convert them on soluble insulin. If not possible give 10 units/ 500 dextrose. If the diabetes is mild and controlled on tablets give 10 units/ alt bottle of dextrose (5%); do not over treat. It is better to have a slightly hyperglycaemic patient rather than hypoglycaemic under anaesthesia. The only sign of caution you get is severe unexplainable tachycardia. Beware of armchair physicians who have not studied patients under anaesthesia or even entered the operation theatre.
  3. Hypertensive patients who are controlled on drugs typically continue the drugs even before operation. If the BP is high, mainly due to fear in most cataract patients, administer 5-10 mg Nifedipine under the tongue on operation table before you start.
  4. High risk patients, toxaemic, gasping with electrolyte imbalance: In this case, your first duty is to keep the patient alive. Avoid Thiopentone or if you do use it for your satisfaction administer homeopathic doses. Forget about Scoline twitchings and awareness of intubation. If Boyle’s Apparatus is available, do nitrous oxide, oxygen induction till eyelash reflex disappears. Give full dose (100 mg) of Scoline, do not compromise. Fractionate the muscle relaxant dose (long acting) or avoid if you can manage with repeated dilute Scoline. The dose needed may be unimaginably small.
  5. Plan your method of anaesthesia well. Do not give spinal if the operation is not likely finish in time. Do not give Thiopentone only for surgeries causing immense pain. Use a combination of drugs with analgesic and amnesic drug.

#26-30: Private Practice Anesthesia- Do’s and Dont’s

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#16-20: Private Practice Anesthesia- Do’s and Dont’s


  1. Never be in a hurry to send the patient back to the ward if the procedure was done under a muscle relaxant. If in doubt try IPPR; if permitted the patient needs reintubation or IPPR with mask till he is completely reversed.
  2. Rising BP; not the colour or consciousness, indicate inadequate reversal. Transfer only if the BP is steady and the patient is conscious.
  3. All patients who have received muscle relaxant (long acting) must be reversed with at least 0.5 to 1 mg. Prostigmin for even a small dose of muscle relaxant.
  4. Patients having long acting spinal anaesthetic drugs must be under observation with written instructions for maintenance of BP in post-operative period.
  5. In patients with known full stomach or even expected full stomach induce with head up tilt, remove the Ryle’s tube after proper suction in different positions. Oxygenate with 100% oxygen. Do not ventilate after Scoline. Ask the surgeon to give tracheal pressure, introduce the laryngoscope blade only when the patient is fully relaxed and intubate. Study your position for intubation (take a flat stool to stand on if necessary) with head up tilt.

#21-25: Private Practice Anesthesia- Do’s and Dont’s

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#11-15: Private Practice Anesthesia- Do’s and Dont’s


  1. Get acclimatized to the nursing home. Find out whether things and injectables are available and where they are stored.
  2. Palpate the vein before puncturing or cannulating. Ask the patient as to where he is taking the injections. Choose the site of puncture depending on nature of operation and the position of the patient during surgery. This is your lifeline. In obese and small children spend some time to find a vein. Do not use the vein on the side where arterio-venous fistula is created.
  3. Listen to the patient his choices and thoughts. Work according to his choice if possible or try to convince him what is best for him.
  4. Children for IV puncture usually cooperate well in sitting position and talking to them explaining what you intend to do. Some children may not cooperate. Avoid premedication by injection as far as possible.
  5. Plan your anaesthesia in such a way that patients are fully conscious as far as possible at the end of procedure. If not make sure they are at least rousable. If the patient is deep observe before sending him back to the ward. Before releasing the patient, try the “Gharpure sign”--The patient on closing both nose and mouth must involuntarily open the mouth to breathe.

#16-20: Private Practice Anesthesia- Do’s and Dont’s

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#6-10: Private Practice Anesthesia- Do’s and Dont’s


  1. Ask the patient about dentures, special drugs and medications, and valuables he may be carrying.
  2. Check that the consent form is signed and witnessed. Make sure there is a separate consent form per operation when the patient visits regularly.
  3. Do not impose your choice of anaesthesia. If there is disagreement discuss and convince the surgeon or the patient. Do not use spinal for investigative procedures and procedures that likely to be repeated very often.
  4. Do not insist on the procedures you are taught in teaching hospital. For example, spinal, general or cannulating a vein in an infant for EUA or IV infusion when not necessary.
  5. Carry your own tourniquet do not expect any help.

#11-15: Private Practice Anesthesia- Do’s and Dont’s

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#1-5: Private Practice Anesthesia- Do’s and Dont’s


  1. Keep calm – very easily said but difficult to practice. There are so many difficulties at each step. Do not bring your worries into the operation theatre.
  2. Keep to your time schedule; it may not always work. Delays by the surgeon, nursing staff, unforeseen emergencies will always delay your schedule. If late or delayed say sorry and start. Do not argue even if you are not in the wrong.
  3. Know your operation schedule the previous night before. In case of doubt, communicate; do not take things for granted. Hernia told to you may mean bilateral hernia, incisional hernia, umbilical hernia or obstructed hernia. Keep the time schedule accordingly. Inform the next surgeon about your delay. Leave the choice to him to arrange another anesthesiologist.
  4. Check your equipment and drugs and replace them immediately.
  5. Always check the notes or find out the information you need from the patient or the surgeon. Check the name and side of operation from the notes and confirm them by asking the patient. Check whether the patient is accompanied by a relative or responsible person.

#6-10: Private Practice Anesthesia-Do’s and Dont’s

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